The MARCH family of RING-finger E3 ubiquitin ligases comprise 11 members that have been reported to play a variety of roles in the downregulation of cell-surface proteins involved in adaptive immunity.The RING-CH domain of MARCH proteins is arm tray for wheelchair thought to ubiquitinate the cytoplasmic tails (CTs) of target proteins, leading to pr
Factors influencing the use of computer-assisted audit techniques in the digital era
Digitalization is a challenge of the current environment, and the digital transition has extended to the audit profession.It affects the technology used by clients and the pressure on auditors by audit regulations to apply and use computer-assisted audit techniques (CAATs).The results of specialized literature indicate that the application and use
PIASgamma is required for faithful chromosome segregation in human cells.
BACKGROUND:The precision of the metaphase-anaphase transition ensures stable genetic inheritance.The spindle checkpoint blocks anaphase onset until the last chromosome biorients at metaphase plate, then the bonds between sister chromatids are removed and disjoined chromatids segregate to the spindle poles.But, how sister separation is triggered is